Thromboembolic disease is the blockage of veins in the deep venous system. When these veins become blocked, the result is pain, inflammation and an increase in the diameter or volume of the limb. These clots may stay in the vein or may break away, causing a PULMONARY EMBOLISM. Embolism, or thromboembolism, can be a very serious complication that leads to respiratory failure and even death.
A clot in the limb can lead not only to a pulmonary embolism but also to lasting after-effects such as post-thrombotic syndrome. A pulmonary embolism occurs when thrombotic material travels from a vein to the lung, causing respiratory failure that can be fatal
Post-thrombotic or post-phlebitic syndrome causes discolouration of the skin on the legs, pain and chronic swelling, and can lead to ulcers that are difficult to heal.




